项目介绍

2025年5月14日

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:

• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 360 employees and approximately 450 million SEK in total assets

The van der Post lab is seeking a postdoctoral fellow to join our team to investigate how microbial metabolites regulate intestinal stem cell proliferation.

Subject area 

Mucosal biology

Subject area description 

Intestinal epithelial renewal is maintained by constant proliferation of colonic stem cells, essential for functioning and barrier integrity. Despite of evidence that our microbiota affects epithelial renewal, the effects and mechanisms regulating stem cell proliferation is known for a relatively low number of metabolites. Revealing how microbial metabolites can regulate proliferation of stem cells is of importance for defining epithelial renewal and regeneration during intestinal homeostasis and disease, such as ulcerative colitis. With the overall aim to develop novel strategies to modulate intestinal stem cell proliferation via the diet or supplements.

Duties 

In this project, the candidate will investigate how epithelial renewal is regulated by the presence and metabolic activity of the microbiome, focusing specifically on the role of microbial metabolites. The goal is to identify key regulators of intestinal stem cell proliferation and elucidate the mechanisms by which microbial signals influence epithelial regeneration. We will apply various complementary techniques to explore this question to enhance our understating of the intricate interaction between the host and microbiota.

Eligibility 

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

Assessment criteria 

The ideal candidate will have a strong background in epithelial cell biology, with experience in culturing primary intestinal cells and applying high-throughput screening methodologies. Experience with techniques such as proteomics, advanced microscopy, and in vivo models is highly desirable. Great emphasis will be placed on the candidate’s personal suitability for the position and clear interest in the subject area. Good knowledge of English, both written and spoken, is necessary.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.

Employment 

The employment is full time and temporary, two years with the possibility of one year’s extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 

If you have any questions about the position, please contact Sjoerd van der Post, Researcher, +46 793367872, sjoerd.van.der.post@medkem.gu.se.

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

– A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

– A CV including a list of publications

– Contact details of two references

– Proof of completed PhD

Applications must be received by: 2025-06-03

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/