项目介绍

2025年2月2日

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Llorens laboratory offers a vibrant, stimulating and international environment. We are part of the Department of Cell and Molecular Biology at the Karolinska Institute in Stockholm, Sweden, one of the world’s leading medical universities. The lab is located in Biomedicum, one of Europe’s largest laboratories with ultramodern facilities and rich opportunities for collaboration and career development.

Systems regenerative neurobiology – Enric Llorens Group

The doctoral student project and the duties of the doctoral student

We are seeking a highly motivated and self-driven doctoral student with a keen interest in CNS regeneration to develop innovative pro regenerative strategies in the context of CNS injury.

Our lab is interested in stimulating regeneration in the mammalian central nervous system. We aim to uncover the principles of cell fate regulation in models of efficient repair and repurpose them to enhance repair in adult stages when regeneration fails. We use a multidisciplinary approach that involves stem cell biology, systems biology, computational biology, molecular engineering and mouse models of disease.

The current project will use in vivo gene delivery to screen and identify genes that positively impact repair processes in models of central nervous system damage and degeneration. The project has a focus on novel gene delivery technologies, gene regulation and glial biology, applied to explore mechanisms and targeted therapeutic strategies that support central nervous system repair.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirementYou meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for driven candidates, with a solid educational background in biotechnology, biomedicine or biology and a keen interest in neuroscience/regenerative medicine. A documented ability to independently carry out experiments/small research projects is required, as are good communication skills in spoken and written English. Experience with central nervous system lesion models in rodents, molecular engineering, advanced viral gene delivery methods, single cell genomics, and/or bioinformatics will be considered an advantage.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.