项目介绍

2024年12月18日

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

At the Department of Rheumatology and Inflammation Research, at the Institute of Medicine, the main research areas are inflammation and inflammatory diseases irrespective of whether they are caused by allergies, infections or are autoimmune diseases. The aim is to investigate the underpinning mechanisms behind the inflammation. Several of our researchers also work as senior consultants at the clinics at Sahlgrenska University Hospital, which is a great advantage especially for translational research.

Professor Lill Mårtensson-Bopp, expert in B cell immunology, and professor/Chief Physician in rheumatology Inger Gjertsson, have a long-standing collaboration where they study the significance of different B-cell populations in the pathogenesis of rheumatoid arthritis (RA). Together, they have three PhD students, two postdocs, a research engineer, a bioinformatician and a statistician. Lab meetings are held regularly, and the department of rheumatology and inflammation research holds regular seminars. Infrastructure for clinical research, single-cell RNA sequencing, flow cytometry, and advanced microscopy is established.

Subject area 

Rheumatology 

Subject area description 

RA is a chronic autoimmune disease affecting 0.5-1% of the population, which can lead to disability and reduced life expectancy. In different projects we investigate the development of B cells and different B-cell populations and their role in RA pathogenesis. This study aims to identify different populations in the bone marrow using sc-RNA and V(D)J sequencing, flow cytometry and other relevant methods to define their gene expression profiles, antibody repertoires, and clinical relevance. The longterm goal is to advance therapeutic precision in RA treatment. 

Duties 

Job assignments include handling of human tissues and blood, sc-RNA and V(D)J sequencing flow cytometry, cell culture, analyses using molecular biological and immunological methods. Management and analysis of data, compiling data for publication as well as applying for research funding are also included. In addition to this the assignment includes presenting results and actively participating at seminars and conferences, writing manuscripts and supervision of students. 

Eligibility 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree in a relevant subject, or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

Assessment criteria 

To be a successful candidate you are required to have a PhD in biology, molecular biology, medicine or a closely related field, good knowledge in immunology and good knowledge of flow cytometry and very good knowledge, understanding and documented experience in analysing sc-RNA and V(D)J data using various programs, e.g., Cellranger, Seurat, and advanced R programming, as well as experience in handling and analyzing public sc-RNA/V(D)J data sets.

You shall have the ability to perform common routine analyses in an immunological laboratory, proven experience in handling human blood and tissue samples, ability to work independently and have good interpersonal skills. You shall also have excellent knowledge of English, both spoken and written. It is meritorious if you have good knowledge of rheumatology and previous experience in scientific publishing.

Great emphasis is placed on personal suitability and personal characteristics such as a structured approach, teamwork skills and good sense of initiative. 

Employment 

Type of employment: Fixed-term employment, 24 months
Extent: 100 %
Location: Institute of Medicine, Gothenburg
First day of employment: As soon as possible or according to agreement    

Contact information 

Lill Mårtensson-Bopp
Professor
+46(0)70-3640068
lill.martensson@rheuma.gu.se

Inger Gjertsson
Professor/Chief Physician
+46(0)730-246725
inger.gjertsson@rheuma.gu.se

Mattias Svensson
Head of Department
+46(0)31-7866706
mattias.svensson@rheuma.gu.se  

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande  

Application 

Please attach PhD certificate with the application, if the PhD certificate has not yet been issued, it needs to be attached latest at the time when the employment decision is to be made.

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

Applications must be received by: 2025-01-06

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/