查尔姆斯理工大学

Postdoc in AI-based design of bacterial protein kinase inhibitors

项目介绍

The Mijakovic lab at Chalmers SysBio (Mijakovic Lab | Chalmers) is recruiting a postdoctoral fellow who will contribute to AI-driven development of inhibitors for bacterial protein-tyrosine kinases. Our interdisciplinary and international group offers a supportive, collaborative and dynamic working environment. 

About us 

The Department of Life Sciences conducts research, innovation, and education to enable a biobased society and improve human health. We explore how biological systems, and innovative technologies can be used to convert biomass into valuable products. We use advanced computational technologies to discover how biomolecules and organisms function and interact. We pioneer new methods for prediction, prevention, diagnostics and treatment of diseases. 

At the Division of Systems and Synthetic Biology biologists, chemists, mathematicians, and engineers work together with the goal of understanding and quantitatively describing the complex functioning of living organisms. We develop technologies that contribute to human and planetary health. 

About the research project

Bacterial protein-tyrosine kinases (BY-kinases) control bacterial biofilm formation, and they have no homologues in humans. This makes BY-kinases a promising target for development of new antibiotics. We have recently discovered a natural mechanism of BY-kinase inhibition based on protein-protein interactions (Connection between protein-tyrosine kinase inhibition and coping with oxidative stress in Bacillus subtilis | PNAS). Based on this breakthrough, we now wish to develop synthetic BY-kinase inhibitors that will be capable of inhibiting biofilm formation in various bacterial pathogens. We are looking for an expert in generative AI who will work alongside an experimental biologist in our group, on jointly designing, testing and optimizing such BY-kinase inhibitors.

 
Who we are looking for 

The following requirements are mandatory: 

  • A Doctoral degree or equivalent in disciplines related to computational biology. This eligibility requirement must be met no later than the time the employment decision is made.  
  • Strong written and verbal communication skills in English. 
  • Experience with the use of generative AI to solve biological questions.

The following experience will strengthen your application: 

  • Experience with molecular biology.
  • Experience with protein structures.
  • Experience with bacterial infections.

What you will do 

  • Carry out the computational work of the project described above.
  • Collaborate tightly with the experimental biologist working in the same project, and other members of the Mijakovic lab.
  • Contribute to writing peer-reviewed papers, and grant applications, if opportunity arises.  
  • Supervise MSc students if opportunity arises. 
  • If you are interested in teaching, it will be possible to arrange some participation in undergrad courses. 

The position is meritorious for future roles in academia, industry, or the public sector. 

Contract terms  

The position is a temporary full-time employment for two years. 

The position requires physical presence throughout the entire employment. A valid residence permit must be presented by the start date, otherwise the offer may be withdrawn. 

What we offer 

  • As a postdoc at Chalmers, you are an employee and enjoy all employee benefits. Read more about  working at Chalmers  and our benefits  for employees. 
  • A dynamic and inspiring working environment in the coastal city of Gothenburg
  • Read more about Sweden’s generous parental leave, subsidized day care, free schools, healthcare etc at Move To Gothenburg. 

Chalmers is dedicated to improving gender balance and actively works with equality projects, such as the GENIE Initiative for gender equality and excellence. We celebrate diversity and consider equality and inclusion as fundamental aspects of all our activities. 

If Swedish is not your native language, Chalmers offers Swedish courses to help you settle in. 

Application procedure 

The application should be written in English be attached as PDF-files, as below. Maximum size for each file is 40 MB. Please note that the system does not support Zip files. 

CV 

  • A comprehensive CV, including education and a complete list of publications.  

Personal letter 

  • A brief introduction about yourself. 
  • A summary of your previous research fields and key research outcomes. 
  • An outline of your future goals and research focus. 

Use the button at the foot of the page to reach the application form.  

A background check may be conducted as part of the application process.

Please note: The applicant is responsible for ensuring that the application is complete. Incomplete applications and applications sent by email will not be considered. Contact details to references will be requested after the interview. 

We welcome your application no later than 15 May 2026 

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截止日期 2026-05-15
查尔姆斯理工大学

院校简介

查尔姆斯理工大学是一所以工程技术、自然科学和建筑学的教育与研究为主旨的欧洲顶尖理工院校。
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联系方式

电话: +46 (0)31-772 10 00

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