哥德堡大学

Medical Science – Genetics and biomarkers in aging and dementia

项目介绍

The University of Gothenburg tackles society’s challenges with diverse knowledge. 53 500 students and 6 500 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Department of Psychiatry and Neurochemistry is located at the Institute of Neuroscience and Physiology at the Faculty of Health Care Sciences at Sahlgrenska Academy, University of Gothenburg. At the Department research is conducted on human behaviour, neuropsychiatric processes as well as psychiatric treatment and diagnosis in close collaboration with Västra Götaland region and a number of international partners. We participate in the undergraduate programmes in Medicine and within The National Research School in Psychiatry/Southwest Sweden. At the Department there are some 15 research groups and four research centers.

Project title: Genetic factors and neurobiological markers in relation to aging, with a specific focus on longevity and dementia

Job assignments

The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies

Project: The average life expectancy in Sweden is increasing and is now higher than ever. As the population is getting older the number of individuals suffering from dementia will increase. We know that both the chance to reach a very old age and the risk of getting dementia are, to a high extent, driven by genetic factors. However, a lot of work remains to understand how genetic risk profiles influence aging and how they relate to neurobiological markers for dementia.

The aim of the PhD-project is to study genetic risk profiles and neurobiological markers (seen in CSF, blood and on brain-MRI) in relation to aging, with a specific focus on longevity and dementia. The project will be of importance for understanding disease pathogeneses, but does also have potential to contribute with important knowledge when it comes to prevention and precision medicine. The project will be conducted at the Research Group for Neuropsychiatric Epidemiology (EPINEP). It is important that the PhD student has a good understanding of how population-based studies works, as the project mainly will be based on the interdisciplinary population-based study of elderly people in Gothenburg. The PhD student is expected to work independently with processing and analyzing of data, which partly include large scale genetic data. The PhD student is expected to be able to use softwares and operational systems for large scale data, such as Python, R and Linux. It is an advantage if the PhD-student has experience of processing large scale data within the areas of ageing, brain health, genetics and neurobiological markers, and is able to use softwares specifically developed for genetic analyses, such as Plink, VCFtools, BCFtools, PRSice and PRS-CS.  

Third-cycle studies are equivalent to four year full-time and lead to a Degree of Doctor. Those appointed to doctoral studentships shall primarily devote themselves to their studies. Those appointed to doctoral studentships may, however, work to a limited extent with educational tasks, research and administration (departmental duties). Before a PhD degree has been awarded, duties of this kind may not comprise more than 20 per cent of a full-time post.

Eligibility

To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements.

A person meets the general entry requirements for third-cycle studies if he or she:
1. has been awarded a second-cycle qualification
2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or
3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad

A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies

Assessment

In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for:
– specific knowledge and skills within the subject area and related research fields
– experience of scientific theory and relevant research methodology
– scientific analysis and presentation verified through thesis, degree project, scientific journals or the like.

Employment

After admission to third-cycle studies you will be appointed to doctoral studentship. Regulations for employment of doctoral students are given in SFS 1993:100. The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. A person may be appointed to a doctoral studentship for a total of eight years. The total employment period may, however, not exceed the time corresponding to full-time third-cycle study for four years.

Location: Sahlgrenska Academy, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry. Extent: 100%. First day of employment: as agreed.

Salaries for doctoral students are regulated in a local agreement at the University. 

For further information regarding the position

For more information about the project please contact the principal supervisor, 
Anna Zettergren, Associate Professor, Institute of Neuroscience and Physiology,
phone: +46 701498414, e-mail: anna.zettergren@neuro.gu.se 

Unions

Union representatives at the University of Gothenburg:
https://www.gu.se/en/about-the-university/work-at-the-university-of-gothenburg/how-to-apply

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

You must include the following, in pdf format

  • Personal letter
  • CV
  • Diploma and transcripts showing that you meet with the general entry requirement
  • Proof of completion of  English 6 course or the acquired equivalent knowledge through previous studies

If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier 

If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.

For information on what you need to submit in order to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/

Closing date: 2021-09-30

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截止日期 2021-09-30
哥德堡大学

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