The Division of Pharmacoepidemiology and Clinical Pharmacology is looking for a PhD candidate in pharmacoepidemiology for a full-time 4-year research position. The position involves 90% research time and 10% teaching activities within the division.
Regulatory authorities are responsible for safeguarding the positive benefit-risk balance of drugs that go on the market. They do so by intervening when drug safety concerns occur, for example, by restricting access to these drugs. These interventions can have unintended impacts on public health. As a core task, you will address the challenges of using real-world data to measure the impact of drug regulation on drug prescription and clinical outcomes.
The project specifically aims to examine the (un)intended consequences of regulatory interventions such as drug withdrawals and warnings on use and prescribing in clinical practice. Unintended outcomes of regulatory interventions are not always foreseen. Restricting the use of one medicine can lead to the increased use of another. Evidence on the impact of these types of regulatory interventions on prescribing, drug use, and clinical outcomes is limited.
The project is a multidisciplinary collaboration where you will engage and collaborate with regulators, health care professionals, patients, pharmacoepidemiologists, and applied data scientists, to identify and assess the (un)intended impacts of different regulatory interventions downstream in clinical practice. You will learn to apply robust methodologies in large real-world health care databases for the purpose of better understanding and/or predicting the (un)intended impact of interventions. The results of this PhD project will generate approaches, that can be used to support clinical and regulatory decision making.
We are looking for a candidate with:
- an MSc in pharmacy, medicine, epidemiology, data science, biostatistics, or another relevant quantitative field;
- a strong interest in pharmaceutical sciences;
- practical experience with data analysis (using R, SAS or Stata, etc.);
- academic writing experience;
- the ability to work within multidisciplinary teams;
- fluency in English, both in speech and writing.
- a full-time position for 4 years;
- a full-time gross salary starting at €2,395 in the first year and increasing to €3,061 in the fourth year (scale P Collective Labor Agreement Dutch Universities (cao));
- benefits including 8% holiday bonus and 8.3% end-of-year bonus;
- a pension scheme, partially paid parental leave, and flexible employment conditions based on the Collective Labor Agreement Dutch Universities.
In addition to the employment conditions laid down in the cao for Dutch Universities, Utrecht University has a number of its own arrangements. For example, there are agreements on professional development, leave arrangements, and sports. We also give you the opportunity to expand your terms of employment via the Employment Conditions Selection Model. This is how we like to encourage you to continue to grow.
More information about working at the Faculty of Science can be found here.
About the organization
As a PhD student, you will be employed at the Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences of the Faculty of Science at Utrecht University.
The division of Pharmacoepidemiology & Clinical Pharmacology consists of a multidisciplinary team of internationally oriented Researchers. The mission of the division is to improve the safe and effective use of medicines by patients and society. Our research contributes to a better understanding of the variability in medicines’ use and patient outcomes, both from a clinical, policy, and methodological perspective.
Innovative observational pharmacoepidemiologic methods are applied and evaluated to obtain reliable information on the benefits and harms of medicines after marketing in real life. Methodological innovations are inspired by relevant research questions in clinical practice, pharmaceutical policy, and regulation. The beneficial and adverse effects of pharmacotherapy are studied in outpatient as well as in hospital settings, linking both exposure and outcome data from various sources (clinical, pharmacy, laboratory, patient). Real-world problems in clinical practice are investigated and thereby immediately relevant to patients and health care providers.
At the Faculty of Science, there are 6 departments to make a fundamental connection with: Biology, Chemistry, Information and Computing Sciences, Mathematics, Pharmaceutical Sciences, and Physics. Each of these is made up of distinct institutes that work together to focus on answering some of humanity’s most pressing problems. More fundamental still are the individual research groups – the building blocks of our ambitious scientific projects.
Utrecht University is a friendly and ambitious university at the heart of an ancient city. We love to welcome new scientists to our city – a thriving cultural hub that is consistently rated as one of the world’s happiest cities. We are renowned for our innovative interdisciplinary research and our emphasis on inspirational research and excellent education. We are equally well-known for our familiar atmosphere and the can-do attitude of our people. This fundamental connection attracts Researchers, Professors and PhD candidates from all over the globe, making both the university and the Faculty of Science a vibrant international and wonderfully diverse community.
If you have any questions, please contact Dr. H. Gardarsdottir (H.Gardarsdottir@uu.nl).
Do you have a question about the application procedure? Please send an email to email@example.com.
Everyone deserves to feel at home at our university. We welcome employees with a wide variety of backgrounds and perspectives. If you have the expertise and the experience to excel in this role, then simply respond via the “Apply now” button! Please enclose:
- your letter of motivation;
- your curriculum vitae;
If this specific opportunity isn’t for you, but you know someone who may be interested, please forward this vacancy to them.
Please note: Due to the current situation regarding the Coronavirus (COVID-19) the process of selection and interviews is subject to change. Initial interviews will most likely be conducted online.