If you would like to contribute to the green transition, you now have the chance. A PhD position is available in the Protein Chemistry and Enzyme Technology section at the Department of Biotechnology and Biomedicine. The research project “Substrate-binding domains as facilitator for enzymatic waste management of man-made polymeric materials” has been granted by Independent Research Fund Denmark. The first part of the project focuses on the identification of substrate-binding domains, which can bind to polymeric materials, while the second task is to fuse these domains to enzymes already capable to degrade polymeric materials, albeit inefficiently.
Responsibilities and qualifications
Your tasks will be to:
- Identify substrate-binding domains to include in a binding screen.
- Establish the screening methods
- Characterise selected substrate-binding domains and optimize binding through different protein engineering strategies
- Fuse identified substrate-binding domains with selected enzymes and characterize the effect
Ideally you should have the following qualifications:
- Knowledge of a programming language
- Experience in bioinformatics analysis
- Interest in experimental work, including recombinant protein production and purification, enzymatic assays, protein-ligand interaction analysis, and protein stability analysis
The project is interdisciplinary in nature, and a part of the project will involve development of screening methods, so we are looking for a person, who are independent and creative. You will be joining a young team dedicated to understand and develop new enzymes useful in industrial biotechnology.
You must have a two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree.
Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.
The assessment of the applicants will be made by Assist. Prof. Marie Sofie Møller and Prof. Peter Westh.
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.
You can read more about career paths at DTU here.
Further information may be obtained from Marie Sofie Møller, tel.: +45 45252741, email@example.com
You can read more about the Department of Biotechnology and Biomedicine at www.bioengineering.dtu.dk and about the Section for Protein Chemistry and Enzyme Technology at https://www.bioengineering.dtu.dk/english/researchny/research-sections/section-for-protein-chemistry-and-enzyme-technology.
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.
Your complete online application must be submitted no later than 20 June 2021.
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply online”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include:
- A letter motivating the application (cover letter)
- Curriculum vitae
- Grade transcripts and BSc/MSc diploma
- Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)
You may apply prior to obtaining your master’s degree but cannot begin before having received it.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.