项目介绍

2026年4月11日

Our lab is seeking a PhD student to apply antibody-based, multiplexed imaging tools to develop spatiotemporal protein maps of human cells and tissues, within the framework of the Human Protein Atlas (HPA). The project focuses on understanding dynamic protein regulation and cell morphology in response to cellular perturbations and activation.

Our research focuses on spatial proteomics and cell biology, bridging bioimaging and proteomics to explore fundamental aspects of human cell biology at the single-cell level. Using an antibody-based approach, we systematically investigate how human proteins are distributed in time and space, how variations in their localization contribute to cell type specificity, and how deviations in protein localization may lead to disease.

In this project, you will develop and apply cutting-edge tools and machine learning techniques to model spatial multi-omics data. The aim is to advance our understanding of protein dynamics at the single-cell level and contribute to a broader understanding of cellular processes. You will also use computational image analysis to study variations in protein spatiotemporal expression patterns in relation to the perturbations and other deterministic factors.

The starting date is open for discussion, though ideally, we would like the successful candidate to start as soon as possible. The placement for this PhD position will be at Science for Life Laboratory in Solna in Stockholm, Sweden(https://www.scilifelab.se), a national centre for molecular biosciences with focus on health and environmental research

Supervision: Prof. Emma Lundberg and Dr. Diana Mahdessian is proposed to supervise the doctoral student. Decisions are made on admission

Admission requirements

To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:

• passed a second cycle degree (for example a master’s degree), or
• completed course requirements of at least 240 higher education credits, of which at least 60 second-cycle higher education credits, or
• acquired, in some other way within or outside the country, substantially equivalent knowledge
• A suitable background for this position would be a master’s degree e.g. in Biomedicine, Biotechnology, Molecular life Sciences or related field.

In addition to the above, there is also a mandatory requirement for English equivalent to English B/6.

Selection

In order to succeed as a doctoral student at KTH you need to be goal oriented and persevering in your work. During the selection process, candidates will be assessed upon their ability to:

• independently pursue his or her work
• collaborate with others,
• have a professional approach and
• analyze and work with complex issues.
• Excellent writing and communication skills in English are required. Experience in multiplexed imaging data analysis is a merit

After the qualification requirements, great emphasis will be placed on personal skills. 

Target degree: Doctoral degree

Information regarding admission and employment

Only those admitted to postgraduate education may be employed as a doctoral student. The total length of employment may not be longer than what corresponds to full-time doctoral education in four years’ time. An employed doctoral student can, to a limited extent (maximum 20%), perform certain tasks within their role, e.g. training and administration. A new position as a doctoral student is for a maximum of one year, and then the employment may be renewed for a maximum of two years at a time. 

As a doctoral student, you are entitled to a workplace with many employee benefits and monthly salary according to KTH’s Doctoral student salary agreement. Read more about Doctoral studies (PhD) | KTH | Sweden.

Union representatives

Contact information forunion representatives.

Doctoral Student’s network (Students’ union on KTH Royal Institute of Technology)

Contact information forPhD chapter.

To apply for the position

Apply for the position and admission through KTH’s recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Applications must include the following elements:

• Copies of diplomas and grades from previous university studies and certificates of fulfilled language requirements (see above). Translations into English or Swedish if the original document is not issued in one of these languages.Copies of originals must be certified.
• CV including your relevant professional experience and knowledge.
• Application letter with a brief description of why you want to pursue research studies, about what your academic interests are and how they relate to your previous studies and future goals. (Maximum 2 pages long)
• Representative publications or technical reports. For longer documents, please provide a summary (abstract) and a web link to the full text.

Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/Central European Summer Time).

Other information

For information about processing of personal data in the recruitment process.

It may be the case that a position at KTH is classified as a security-sensitive role in accordance with the Protective Security Act (2018:585). If this applies to the specific position, a security clearance will be conducted for the applicant in accordance with the same law with the applicant’s consent. In such cases, a prerequisite for employment is that the applicant is approved following the security clearance.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.