项目介绍

2026年9月12日

We are offering a three-year PhD fellowship in computational pharmacology and pharmaceutical data science commencing 15 October 2026 or as soon as possible thereafter.

Our group and research
The project is based at the Department of Drug Design and Pharmacology and connected to the Center for Pharmaceutical Data Science Education (CPDSE). The group has broad expertise encompassing structural bioinformatics, statistical genetics, cheminformatics, database development, and the application of machine learning approaches.

Project description
The PhD project will investigate how genetic variants alter GPCR dynamics and drug responses. The candidate will use atomistic MD simulations to identify biophysical descriptors of receptor function and integrate these with machine-learning approaches to predict ligand- and variant-specific pharmacological outcomes. The dopamine D2 receptor will serve as the primary model system.

Principal supervisor
Associate Professor Alexander Hauser, Department of Drug Design and Pharmacology

Start
15 October 2026

Duration
3 years as a PhD student

Our department
The Department of Drug Design and Pharmacology is committed to research-based education and interdisciplinary research that supports the development and understanding of chemical and pharmacological properties of drugs and drug targets at the highest level for the benefit of society. We work as part of a dynamic academic community of research, education, and innovation within the Pharmaceutical Sciences, bridging Health Sciences and Life Sciences.

Information about the Department can be found here.

Job description
Your key tasks as a PhD student at the Faculty of Health and Medical Sciences are:

• Carrying out an independent research project under supervision
• Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points
• Participating in active research environments including a stay at another research team, preferably abroad
• Obtaining experience with teaching or other types of dissemination related to your PhD project
• Teaching undergraduate students in pharmaceutical sciences
• Writing a PhD thesis on the grounds of your project

PhD Programme description
The PhD programme is a three-year full-time research education within the framework of the 5+3 scheme, intended for candidates holding a relevant academic degree within the project’s subject area, such as bioinformatics, computational biology or computational chemistry.

Qualifications
If you have completed your academic education in Denmark, admission to the PhD programme requires a relevant Master’s degree (equivalent to 180 ECTS BSc + 120 ECTS MSc).

If you have an academic education from abroad, you must have either a degree equivalent to a Danish master’s degree (180 ETCS + 120 ECTS MSc), or at a minimum, a bachelor’s degree equivalent to a Danish bachelor’s degree (180 ECTS) and be academically qualified at master’s level.

As part of the assessment of whether you meet the educational requirements, you must also achieve a positive academic evaluation and be assessed as the best qualified for the position.

Profile
We are looking for a highly motivated and ambitious bioinformatician, data scientist, or machine learning specialist proficient with biologically driven questions, ideally experienced in MD simulations.

Other important criteria are:

• Relevant experience with molecular modelling, molecular dynamics simulations and/or analysis of molecular simulation data
• Excellent programming skills, preferably in Python including code versioning in GitHub
• Experience with statistical analysis and/or machine-learning methods
• Knowledge of protein structure, structural bioinformatics, or molecular interactions; experience with GPCRs or membrane proteins is an advantage
• A curious mindset with a strong interest in computational pharmacology, GPCRs, and pharmaceutical data science
• Knowledge of cell biology, protein structures, and evolution
• Strong written and spoken English and good communication and collaboration skills

The person will be required to relocate to Copenhagen and key responsibilities will include: establishing research ideas together with the principal investigator, leading the research project on a day-to-day basis, presenting research in internal meetings and international conferences, taking an active part in manuscript writing, and translating new knowledge in the subject area into research activity. There will be the opportunity to supervise more junior group members and contribute to teaching and dissemination activities.

Place of employment
The place of employment is at the of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen as well as the newly founded Center for Pharmaceutical Data Science Education (CPDSE). We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include a competitive computational core facility and modern environment. Moreover, we are part of the cluster for Integrated Structural Biology (ISBUC), Center for Health Data Science (HeaDS), Science AI Centre (AICenter), and the pharmaceutical informatics research section (link).

Terms of employment
The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 3 years.

The employment is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project to the Graduate School of Health and Medical Sciences.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2025) and the Faculty’s rules on achieving the degree.

The PhD student is expected to be affiliated to the graduate programme in pharmaceutical sciences, Drug Research Academy.

Salary, pension, and terms of employment are in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 34,700 DKK/Roughly 4,650 EUR (August 2026) plus pension.

Application procedure
Your application, in English, must be submitted electronically by clicking “Apply now” below and must include the following documents in PDF format:

1. Motivated letter of application (max. one page)
2. CV incl. education, experience, language skills and other skills relevant for the position
3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in a language other than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science. Applicants with a Master´s degree from abroad should also enclose a short description of the grading scale used
4. Publication list (if possible)
5. Other information to consider: References and recommendations (if possible)

The deadline for applications is 26 September 2026, 23.59 (CEST)
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorised recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 41.

You can read about the recruitment process here.

Questions
For further information, applicants may contact the principal supervisor Alexander Hauser, e-mail:  alexander.hauser@sund.ku.dk, phone: +45 3533 2556 or PhD coordinator Marianne W. Jørgensen, e-mail: marianne.joergensen@sund.ku.dk, phone: +45 3533 6449.

General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website.

For more information on working and living in Denmark visit International staff mobility and Work in Denmark.