项目介绍

2026年7月9日

PhD-position

At the Faculty of Medicine, Department of Clinical Science, a full-time PhD-position is available for a period of three (3) years. The position is part of the project “AIRE, IL-12 and interferon-g; Drivers of immune tolerance and T cell function”, funded by the Norwegian Research Council

About the project/work tasks:

• The project is based on how AIRE, IL 12 and IFN γ cooperate to establish immunological tolerance in the thymus, and how failure of these mechanisms can lead to autoimmune diseases. AIRE mutations cause severe autoimmunity, and both mouse models and patient data show disruptions in IL 12/IFN γ signalling. The project seeks to understand how these factors affect the thymus, T cell development and immune tolerance, and investigates whether targeted modulation of the IL 12/IFN γ axis can restore immune balance. This combines basic research, genetics and translational immunology.
• The position involves work with advanced mouse models, including a new combined AIRE and IL 12 deficient model to study autoimmunity. You will perform analyses of thymus, T cells and peripheral immune cells using flow cytometry, single cell RNA sequencing and CODEX based tissue imaging. The work also includes functional characterization of genetic variants identified in patient cohorts, as well as testing of immunomodulatory drugs that affect IL 12/IFN γ signalling. the role of IL-12 and interferon gamma in AIRE-mediated immune tolerance

Qualifications and personal qualities:

• The applicant must possess a Master`s degree or an equivalent in molecular biology, immunology, cell biology, or biomedical sciences or similar. 
• The candidate must have documented laboratory experience from a molecular biology laboratory.
• Experience with relevant experimental methods such as flow cytometry, immunological assays, or quantitative PCR will be considered positive.
• Interest in, or experience with animal research will be considered as positive. 
• Experience from relevant research projects will be considered as positive 
• The candidate should demonstrate the ability to work independently and in a structured manner, while also being capable of effective collaboration with others
• The applicant must exhibit both the ability and motivation to undertake a PhD project.
• Fluency in both oral and written English is required, see documentation requirements for further details.

The applicant’s personal suitability for the position is a significant factor in the evaluation.

About the PhD-position (applies to university PhD-positions):

Applicants whose educational qualifications are from countries other than Norway must provide a certified translation of the diploma and transcript of grades to English or a Scandinavian language, if the original documents are not in any of these languagees. It is also required that the applicant submit a review from the Norwegian Directorate for Higher Education and Skills (HK-dir) to verify whether the education in question (bachelor and master’s degree) is of a scope and level that corresponds to the level of a Norwegian master’s degree. Please see https://hkdir.no/en/ for more information about HK-dir’s general recognition. The review process by HK-dir may take some time. Therefore, please submit your application to HK-dir as soon as you decide to apply for the position. If you do not receive a response within the application deadline, you must include documentation from HK-dir confirming receipt of your application. Please note that the automatic recognition offered by HK-dir insufficient and will not be accepted as basis for admission to the PhD programme. Applicants with education from a Nordic country or those with a medical degree from the EEA area and a license to practice medicine in Norway are exempt from the requirement for HK-dir assessment. For more information please refer to the Admission requirements at the Faculty of Medicine | Faculty of Medicine | UiB

Additionally, please review the documentation requirements for language qualifications: http://www.uib.no/en/med/115526/english-language-requirements-phd-admission

Organized research training (PhD program):

The candidate must take part in the University of Bergen approved PhD programme leading to the degree within a time limit of 3 years. Admission to the organized research training (PhD program) at the Faculty is essential for this position. 

Application for admission to the PhD programme, including a project plan outline for the training plan must be submitted no later than three months after the date of commencement.

The PhD-position:

PhD-positions are fixed term positions. You cannot be employed in a PhD-position for more than one fixed term period at the same institution or have had similar employment at an institution in the region

We can offer:

• Exciting development opportunities as part of your role in a strong professional environment
• Salary NOK 600 000 (code 1017) in the state salary scale. For applicants with at least one year of employment in a position as a General Practitioner or Dentist, salary NOK 615 000 (For applicants who are licensed as medical doctors or dentists, documentation of Norwegian authorization must be submitted with the application.). Medical specialist starts on salary NOK 635 000 (For applicants with specialist training, a certificate of specialist approval from the Norwegian Directorate of Health must also be included.)
• Enrolment in the Norwegian Public Service Pension Fund
• Good welfare benefits

Your application must include:

• A brief account of the applicant`s research interests and motivation for applying for the position
• Certified copies of diplomas and transcripts of grades. Applicant whose education is from another country than Norway, need to also attach a certified translation of the diploma and transcript of grades to English or a Scandinavian language, if the original is not in any of these languages. It is also required that the applicant enclose a review from HK-dir (both bachelor and master degree) whether the education in question is of a scope and level that corresponds to the level of a Norwegian master’s degree. Please see https://hkdir.no/en/ for more information about HK-dir’s general recognition. This may take some time and we recommend you to apply as soon as you know you will apply for this position. If no answer within the application deadline, please enclose documentation from HK-dir that they have received your application 
• Documentation of language skills (English)
• Complete list of publications and scientific work you want to be evaluated
• Any publication in your name
• Two references (name and contact information)