荷语区鲁汶大学

PhD student: Investigating metabolic plasticity of human skeletal muscle using novel engineered pluripotent stem cell-based organoids

项目介绍

The Yilmaz Laboratory for Cell Fate Transition Research is part of a broad network of research groups at KU Leuven, which ranks among the world’s top 50 universities, with excellent expertise in cell biology, genomics, bioinformatics, tissue engineering and metabolomics in mammalian cells and in different organisms. As a PhD candidate under the supervision of Prof. Atilgan Yilmaz, you will work in close collaboration with the laboratory of Prof. Ioannis Papantoniou, a leading expert in tissue engineering and biofabrication. You will be a member of the highly international Leuven Stem Cell Institute (https://www.kuleuven.be/samenwerking/scil) and utilize a unique combination of methodologies and experimental tools, including the bioprinting of novel human pluripotent stem cell-derived organoids, measurements of biophysical properties, metabolic assays, CRISPR/Cas9-mediated gene editing, transcriptome analyses, immunostaining and microscopy and in vitro disease models.

Project

You will develop a next-generation skeletal muscle organoid platform derived from human pluripotent stem cells. This bioprinted organoid platform will be used for metabolic and transcriptomic assessment of specific disease models and drug treatments. Metabolic plasticity of this platform will be studied through tissue-level, cellular and molecular characterization in healthy and disease states. 
For publications and research activities of both groups, please visit:https://www.kuleuven.be/wieiswie/en/person/00153792https://www.kuleuven.be/wieiswie/en/person/00078064

Profile

The successful candidate should:• hold a diploma or Master’s degree (from one of the countries of the European Economic Area or Switzerland) in cellular biology, biochemistry or bio-engineering or related biomedical field, with excellent marks.• have lab experience in molecular and cellular biology.• have experience in (or strong will to be trained for and use) next generation sequencing analysis • be structured, highly motivated, ambitious and adaptable to diverse methodologies and interdisciplinary environment.• be fluent in written and spoken English.

Offer

We offer you:
●  a full-time PhD position, pending a positive evaluation by your PhD committee after year 1. Remuneration will be according to the KU Leuven salary scales (https://www.kuleuven.be/personeel/jobsite/en/phd/phd-information#working-conditions).
●  training at the KULeuven, one of the top European Universities, providing an excellent international research environment.
●  opportunities to participate in local and international conferences and thus expand your scientific network.
●  a competitive stipend and benefits based on the KULeuven employment guidelines.
●  the applicant will be fully assisted and encouraged to apply for independent funding such as the FWO PhD Fellowship.

Interested?

For more information please contact Christina Vochten mail: christina.vochten@kuleuven.be.

Your application file should consist of the following documents:CVMotivation letterTwo reference letters.You can apply for this job no later than June 22, 2026 via the online application tool

KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.

项目概览

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欧洲, 比利时 所在地点
带薪岗位制 项目类别
截止日期 2026-06-22
荷语区鲁汶大学

院校简介

鲁汶大学是比利时久负盛名的世界百强名校。
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联系方式

电话: +32 16 324010

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